Let-7-P2b2

MirGeneDB ID

Mmu-Let-7-P2b2

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

House mouse (Mus musculus)

MiRBase ID

mmu-let-7b

Paralogues

Mmu-Let-7-P1b Mmu-Let-7-P1c Mmu-Let-7-P1d Mmu-Let-7-P2a1 Mmu-Let-7-P2a2 Mmu-Let-7-P2a3 Mmu-Let-7-P2b1 Mmu-Let-7-P2b3 Mmu-Let-7-P2c1 Mmu-Let-7-P2c2 Mmu-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2b2 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2b2 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P2b2 Cfa-Let-7-P2b2 Cja-Let-7-P2b2 Cli-Let-7-P2b2 Cmi-Let-7-P2b2 Cpi-Let-7-P2b2 Cpo-Let-7-P2b2 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2b2 Dpu-Let-7 Dre-Let-7-P2b2a Dre-Let-7-P2b2b Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P2b2 Egr-Let-7 Esc-Let-7 Ete-Let-7-P2b2 Gga-Let-7-P2b2 Gja-Let-7-P2b2 Gmo-Let-7-P2b2a Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P2b2 Isc-Let-7 Laf-Let-7-P2b2 Lan-Let-7 Lch-Let-7-P2b2 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2b2 Mal-Let-7-P2b2a Mal-Let-7-P2b2b Mdo-Let-7-P2b2 Mgi-Let-7 Mml-Let-7-P2b2 Mmr-Let-7-P2b2 Mom-Let-7 Mun-Let-7-P2b2 Neu-Let-7-P2b2 Npo-Let-7 Oan-Let-7-P2b2 Obi-Let-7 Ocu-Let-7-P2b2 Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P2b2 Pau-Let-7 Pbv-Let-7-P2b2 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rno-Let-7-P2b2 Rph-Let-7 Sha-Let-7-P2b2 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2b2 Spu-Let-7 Sro-Let-7 Sto-Let-7-P2b2 Tca-Let-7 Tgu-Let-7-P2b2 Tni-Let-7-P2b2a Tni-Let-7-P2b2b Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P2b2c Xla-Let-7-P2b2d Xtr-Let-7-P2b2

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(mm10)

chr15: 85707325-85707399 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2b2)

Let-7-P2a2 chr15: 85706616-85706684 [+] UCSC Ensembl
Let-7-P2b2 chr15: 85707325-85707399 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

GGCCUCCUCCAGAACACGGACACCGCAGGGUGAGGUAGUAGGUUGUGUGGUUUCAGGGCAGUGAUGUUGCCCCUCCGAAGAUAACUAUACAACCUACUGCCUUCCCUGAGGCGCCCAGGGACACAGCUACAUGGA

Get precursor sequence

Structure

        10          20        30        40        50        60       
GGCCUCCUCCAGAACAC--| ACA  G     U                     UCAGGGCAGUGAUG 
                   GG   CC CAGGG GAGGUAGUAGGUUGUGUGGUU              U
                   CC   GG GUCCC UUCCGUCAUCCAACAUAUCAA              U
AGGUACAUCGACACAGGGA^ CGC  A     -                     UAGAAGCCUCCCCG 
   130       120       110        100        90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Yes

Motifs

Tissue expression

Br	Br	Ce	Ce	Em	Em	He	Ki	Li	Lu	Ov	Pa	Sk	Sp	Te

Mature sequence

Mmu-Let-7-P2b2_5p

mirBase accession

MIMAT0000522

Sequence

0- UGAGGUAGUAGGUUGUGUGGUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0000522
TargetScanVert: mmu-let-7b-5p
miRDB: MIMAT0000522

Star sequence

Mmu-Let-7-P2b2_3p*

mirBase accession

MIMAT0004621

Sequence

54- CUAUACAACCUACUGCCUUCC -75

Get sequence

Proposed targets

microrna.org: MIMAT0004621
TargetScanVert: mmu-let-7b-3p
miRDB: MIMAT0004621