Let-7-P2b2

MirGeneDB ID

Mmu-Let-7-P2b2

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

House mouse (Mus musculus)

MiRBase ID

mmu-let-7b

Paralogues

Mmu-Let-7-P1b Mmu-Let-7-P1c Mmu-Let-7-P1d Mmu-Let-7-P2a1 Mmu-Let-7-P2a2 Mmu-Let-7-P2a3 Mmu-Let-7-P2b1 Mmu-Let-7-P2b3 Mmu-Let-7-P2c1 Mmu-Let-7-P2c2 Mmu-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2b2 Ami-Let-7-P2b2 Bge-Let-7 Bpl-Let-7 Bta-Let-7-P2b2 Cfa-Let-7-P2b2 Cgi-Let-7 Cli-Let-7-P2b2 Cmi-Let-7-P2b2 Cpi-Let-7-P2b2 Cpo-Let-7-P2b2 Cte-Let-7 Dan-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2b2 Dpu-Let-7 Dre-Let-7-P2b2a Dre-Let-7-P2b2b Dsi-Let-7 Dya-Let-7 Esc-Let-7 Ete-Let-7-P2b2 Gga-Let-7-P2b2 Gja-Let-7-P2b2 Gmo-Let-7-P2b2a Hme-Let-7 Hsa-Let-7-P2b2 Isc-Let-7 Lan-Let-7 Lch-Let-7-P2b2 Lgi-Let-7 Loc-Let-7-P2b2 Mal-Let-7-P2b2a Mal-Let-7-P2b2b Mdo-Let-7-P2b2 Mml-Let-7-P2b2 Mun-Let-7-P2b2 Npo-Let-7 Oan-Let-7-P2b2 Obi-Let-7 Ocu-Let-7-P2b2 Ovu-Let-7 Pbv-Let-7-P2b2 Pfl-Let-7 Pmi-Let-7 Rno-Let-7-P2b2 Sha-Let-7-P2b2 Sko-Let-7 Spt-Let-7-P2b2 Spu-Let-7 Sto-Let-7-P2b2 Tca-Let-7 Tgu-Let-7-P2b2 Tni-Let-7-P2b2a Tni-Let-7-P2b2b Xbo-Let-7 Xla-Let-7-P2b2c Xla-Let-7-P2b2d Xtr-Let-7-P2b2

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(mm10)

chr15: 85707325-85707399 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2b2)

Let-7-P2a2 chr15: 85706616-85706684 [+] UCSC Ensembl
Let-7-P2b2 chr15: 85707325-85707399 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

GGCCUCCUCCAGAACACGGACACCGCAGGGUGAGGUAGUAGGUUGUGUGGUUUCAGGGCAGUGAUGUUGCCCCUCCGAAGAUAACUAUACAACCUACUGCCUUCCCUGAGGCGCCCAGGGACACAGCUACAUGGA

Get precursor sequence

Structure

        10          20        30        40        50        60       
GGCCUCCUCCAGAACAC--| ACA  G     U                     UCAGGGCAGUGAUG 
                   GG   CC CAGGG GAGGUAGUAGGUUGUGUGGUU              U
                   CC   GG GUCCC UUCCGUCAUCCAACAUAUCAA              U
AGGUACAUCGACACAGGGA^ CGC  A     -                     UAGAAGCCUCCCCG 
   130       120       110        100        90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Yes

Motifs

Tissue expression

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Mature sequence

Mmu-Let-7-P2b2_5p

mirBase accession

MIMAT0000522

Sequence

0- UGAGGUAGUAGGUUGUGUGGUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0000522
TargetScanVert: mmu-let-7b-5p
miRDB: MIMAT0000522

Star sequence

Mmu-Let-7-P2b2_3p*

mirBase accession

MIMAT0004621

Sequence

54- CUAUACAACCUACUGCCUUCC -75

Get sequence

Proposed targets

microrna.org: MIMAT0004621
TargetScanVert: mmu-let-7b-3p
miRDB: MIMAT0004621