Let-7-P2b2

MirGeneDB ID

Cfa-Let-7-P2b2

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Dog (Canis familiaris)

MiRBase ID

cfa-let-7b

Paralogues

Cfa-Let-7-P1b Cfa-Let-7-P1c Cfa-Let-7-P1d Cfa-Let-7-P2a1 Cfa-Let-7-P2a2 Cfa-Let-7-P2a3 Cfa-Let-7-P2b1 Cfa-Let-7-P2b3 Cfa-Let-7-P2c1 Cfa-Let-7-P2c2 Cfa-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2b2 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2b2 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P2b2 Cja-Let-7-P2b2 Cli-Let-7-P2b2 Cmi-Let-7-P2b2 Cpi-Let-7-P2b2 Cpo-Let-7-P2b2 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2b2 Dpu-Let-7 Dre-Let-7-P2b2a Dre-Let-7-P2b2b Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P2b2 Egr-Let-7 Esc-Let-7 Ete-Let-7-P2b2 Gga-Let-7-P2b2 Gja-Let-7-P2b2 Gmo-Let-7-P2b2a Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P2b2 Isc-Let-7 Laf-Let-7-P2b2 Lan-Let-7 Lch-Let-7-P2b2 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2b2 Mal-Let-7-P2b2a Mal-Let-7-P2b2b Mdo-Let-7-P2b2 Mgi-Let-7 Mml-Let-7-P2b2 Mmr-Let-7-P2b2 Mmu-Let-7-P2b2 Mom-Let-7 Mun-Let-7-P2b2 Neu-Let-7-P2b2 Npo-Let-7 Oan-Let-7-P2b2 Obi-Let-7 Ocu-Let-7-P2b2 Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P2b2 Pau-Let-7 Pbv-Let-7-P2b2 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rno-Let-7-P2b2 Rph-Let-7 Sha-Let-7-P2b2 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2b2 Spu-Let-7 Sro-Let-7 Sto-Let-7-P2b2 Tca-Let-7 Tgu-Let-7-P2b2 Tni-Let-7-P2b2a Tni-Let-7-P2b2b Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P2b2c Xla-Let-7-P2b2d Xtr-Let-7-P2b2

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(canFam3_add)

chr10: 20033392-20033467 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2b2)

Let-7-P2b2 chr10: 20033392-20033467 [-] UCSC Ensembl
Let-7-P2a2 chr10: 20034320-20034387 [-] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

GACCCUCCCGCACCCCGGGCACCGGCGGGGUGAGGUAGUAGGUUGUGUGGUUUCAGGGCAGUGAUGUUGCCCCCUCGGAAGAUAACUAUACAACCUACUGCCUUCCCCGAGGAGCCCAGCGACACGUCCCCACGGG

Get precursor sequence

Structure

        10           20        30        40        50        60        
GACCCUCCCGCACCCCG---|  A  GG     U                     UCAGGGCAGUGAUGU 
                    GGC CC  CGGGG GAGGUAGUAGGUUGUGUGGUU               \
                    CCG GG  GCCCC UUCCGUCAUCCAACAUAUCAA               U
GGGCACCCCUGCACAGCGAC^  A  A-     -                     UAGAAGGCUCCCCCG 
    130       120       110         100        90        80        70

Deep sequencing

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3' NTU

Yes

Motifs

Tissue expression

An	An	An	Bl	Ce	Co	He	Hi	Hi	Hy	Ki	Ki	Li	Lu	Ov	Sk	Te	Te

Mature sequence

Cfa-Let-7-P2b2_5p

mirBase accession

MIMAT0009836

Sequence

0- UGAGGUAGUAGGUUGUGUGGUU -22

Get sequence

Proposed targets

TargetScanVert: cfa-let-7b
miRDB: MIMAT0009836

Star sequence

Cfa-Let-7-P2b2_3p*

mirBase accession

None

Sequence

55- CUAUACAACCUACUGCCUUCC -76

Get sequence