Let-7-P2a1

MirGeneDB ID

Hsa-Let-7-P2a1

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Human (Homo sapiens)

MiRBase ID

hsa-let-7a-1

Paralogues

Hsa-Let-7-P1b Hsa-Let-7-P1c Hsa-Let-7-P1d Hsa-Let-7-P2a2 Hsa-Let-7-P2a3 Hsa-Let-7-P2b1 Hsa-Let-7-P2b2 Hsa-Let-7-P2b3 Hsa-Let-7-P2c1 Hsa-Let-7-P2c2 Hsa-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2a1 Ami-Let-7-P2a1 Bge-Let-7 Bpl-Let-7 Bta-Let-7-P2a1 Cfa-Let-7-P2a1 Cgi-Let-7 Cli-Let-7-P2a1 Cmi-Let-7-P2a1 Cpi-Let-7-P2a1 Cpo-Let-7-P2a1 Cte-Let-7 Dan-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2a1 Dpu-Let-7 Dre-Let-7-P2a1a Dsi-Let-7 Dya-Let-7 Esc-Let-7 Ete-Let-7-P2a1 Gga-Let-7-P2a1 Gja-Let-7-P2a1 Gmo-Let-7-P2a1a Hme-Let-7 Isc-Let-7 Lan-Let-7 Lch-Let-7-P2a1 Lgi-Let-7 Loc-Let-7-P2a1 Mal-Let-7-P2a1a Mdo-Let-7-P2a1 Mml-Let-7-P2a1 Mmu-Let-7-P2a1 Mun-Let-7-P2a1 Npo-Let-7 Oan-Let-7-P2a1 Obi-Let-7 Ocu-Let-7-P2a1 Ovu-Let-7 Pbv-Let-7-P2a1 Pfl-Let-7 Pmi-Let-7 Rno-Let-7-P2a1 Sha-Let-7-P2a1 Sko-Let-7 Spt-Let-7-P2a1 Spu-Let-7 Sto-Let-7-P2a1 Tca-Let-7 Tgu-Let-7-P2a1 Xbo-Let-7 Xla-Let-7-P2a1c Xla-Let-7-P2a1d Xtr-Let-7-P2a1

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(hg38)

chr9: 94175962-94176033 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2a1)

Let-7-P2a1 chr9: 94175962-94176033 [+] UCSC Ensembl
Let-7-P2b1 chr9: 94176353-94176429 [+] UCSC Ensembl
Let-7-P2c1 chr9: 94178841-94178915 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

UUCACCCUGGAUGUUCUCUUCACUGUGGGAUGAGGUAGUAGGUUGUAUAGUUUUAGGGUCACACCCACCACUGGGAGAUAACUAUACAAUCUACUGUCUUUCCUAACGUGAUAGAAAAGUCUGCAUCCAGGC

Get precursor sequence

Structure

        10          20        30        40        50        60      
UUCACCCUGGAUGUUCU-  -|   UG     U   GU                UUAGGGUCACACC 
                  CU UCAC  UGGGA GAG  AGUAGGUUGUAUAGUU             \
                  GA AGUG  AUCCU UUC  UCAUCUAACAUAUCAA             C
CGGACCUACGUCUGAAAA  U^   CA     -   UG                UAGAGGGUCACCA 
130       120       110        100        90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Yes

Motifs

Tissue expression

1-	1-	1-	1-	1-	1-	1-	1-	1-	1-	1-	1-	1-	2-	2-	2-	2-	2-	2-	2-	2-	2-	2-	2-	3-	3-	3-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	4-	5-	5-	5-	5-	5-	5-	5-	6-	6-	6-	6-	6-

Mature sequence

Hsa-Let-7-P2a1_5p

mirBase accession

MIMAT0000062

Sequence

0- UGAGGUAGUAGGUUGUAUAGUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0000062
TargetScanVert: hsa-let-7a-5p
TargetMiner: hsa-let-7a-5p
miRDB: MIMAT0000062

Star sequence

Hsa-Let-7-P2a1_3p*

mirBase accession

MIMAT0004481

Sequence

51- CUAUACAAUCUACUGUCUUUC -72

Get sequence

Proposed targets

microrna.org: MIMAT0004481
TargetScanVert: hsa-let-7a-3p
TargetMiner: hsa-let-7a-3p
miRDB: MIMAT0004481