Mir-188-P2

MirGeneDB ID

Hsa-Mir-188-P2

Family name

MIR-188 (all species)

Seed

AUCCCUU

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-188

Paralogues

Hsa-Mir-188-P1 Hsa-Mir-188-P3

Orthologues

Bta-Mir-188-P2 Cfa-Mir-188-P2 Cja-Mir-188-P2 Cpo-Mir-188-P2 Dno-Mir-188-P2 Eca-Mir-188-P2 Laf-Mir-188-P2 Mml-Mir-188-P2 Mmr-Mir-188-P2 Mmu-Mir-188-P2 Ocu-Mir-188-P2 Pab-Mir-188-P2 Rno-Mir-188-P2

Node of Origin (locus)

Eutheria

Node of Origin (family)

Eutheria

Genome context
(hg38)

chrX: 50003517-50003576 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-188-P2)

Mir-188-P1 chrX: 50003167-50003225 [+] UCSC Ensembl
Mir-188-P2 chrX: 50003517-50003576 [+] UCSC Ensembl
Mir-362-P3a-v1 chrX: 50008443-50008504 [+] UCSC Ensembl
Mir-362-P3a-v2 chrX: 50008443-50008504 [+] UCSC Ensembl
Mir-362-P4 chrX: 50008968-50009026 [+] UCSC Ensembl
Mir-362-P5 chrX: 50009735-50009794 [+] UCSC Ensembl
Mir-362-P3b chrX: 50010681-50010742 [+] UCSC Ensembl
Mir-188-P3 chrX: 50013256-50013314 [+] UCSC Ensembl
Mir-362-P6 chrX: 50014612-50014671 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

AGAGCAAGCCCUUCCCUGCUCCCUCUCUCACAUCCCUUGCAUGGUGGAGGGUGAGCUUUCUGAAAACCCCUCCCACAUGCAGGGUUUGCAGGAUGGCGAGCCUCAGCUUUCCUUGCUCUC

Get precursor sequence

Structure

        10          20         30        40        50         
AGAGCAAGCCCUUCCCU--    -| UC   CA  UC         GU      UGAGCUU 
                   GCUC CC  UCU  CA  CCUUGCAUG  GGAGGG       U
                   CGAG GG  AGG  GU  GGGACGUAC  CCUCCC       C
CUCUCGUUCCUUUCGACUC    C^ U-   AC  UU         AC      CAAAAGU 
.       110       100         90        80        70        60

Deep sequencing

Go to detailed chart

Comment

The Dicer cut is consistently +3 across mammals.

3' NTU

Motifs

UG at 5p(-14)

Tissue expression

Dc	Dc	Dr	Dr	Xp	Xp	Bl	Br	Br	Ce	Ce	Co	Fo	He	Ki	Le	Li	Li	Lu	Pa	Pl	Pl	Sk	Sk	Sk	Sm	Sp	Sp	St	Te	Th	Ut

Mature sequence

Hsa-Mir-188-P2_5p

mirBase accession

MIMAT0000457

Sequence

0- CAUCCCUUGCAUGGUGGAGGGU -22

Get sequence

Proposed targets

microrna.org: MIMAT0000457
TargetScanVert: hsa-miR-188-5p
TargetMiner: hsa-miR-188-5p
miRDB: MIMAT0000457

Star sequence

Hsa-Mir-188-P2_3p*

mirBase accession

MIMAT0004613

Sequence

39- CUCCCACAUGCAGGGUUUGCA -60

Get sequence

Proposed targets

microrna.org: MIMAT0004613
TargetScanVert: hsa-miR-188-3p
TargetMiner: hsa-miR-188-3p
miRDB: MIMAT0004613