MirGeneDB 3.0

MirGeneDB ID

Ocu-Mir-145

Family name MIR-145 (all species)
Seed UCCAGUU
Species Rabbit (Oryctolagus cuniculus)
MiRBase ID ocu-mir-145
Paralogues
Orthologues Aca-Mir-145  Ami-Mir-145  Bta-Mir-145  Cfa-Mir-145  Cja-Mir-145  Cli-Mir-145  Cmi-Mir-145  Cpi-Mir-145  Cpo-Mir-145  Dno-Mir-145  Dre-Mir-145  Ebu-Mir-145  Eca-Mir-145  Ete-Mir-145  Gga-Mir-145  Gja-Mir-145  Gmo-Mir-145  Hsa-Mir-145  Laf-Mir-145  Lch-Mir-145  Loc-Mir-145  Mal-Mir-145  Mdo-Mir-145  Mml-Mir-145  Mmr-Mir-145  Mmu-Mir-145  Mun-Mir-145  Neu-Mir-145  Oan-Mir-145  Pab-Mir-145  Pbv-Mir-145  Pma-Mir-145  Rno-Mir-145  Sha-Mir-145  Spt-Mir-145  Sto-Mir-145  Tgu-Mir-145  Xla-Mir-145-P1  Xla-Mir-145-P2  Xtr-Mir-145 
Node of Origin (locus) Vertebrata
Node of Origin (family) Vertebrata
Genome context
(oryCun2_add)
chr3: 31259937-31259996 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-145)
Mir-143 chr3: 31258615-31258669 [+] UCSC Ensembl
Mir-145 chr3: 31259937-31259996 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
ACGGCCACGCUUGCCCACCUUGUCCUCGGGGUCCAGUUUUCCCAGGAAUCCCUUAGAUGCUAAGAUGGGGAUUCCUGGAAAUACUGUUCUUGAGGUCAUGGUUUCACAGCUGGCCCAGCG
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Structure
        10          20        30        40        50          
ACGGCCACGCUUGCCCA--| U  U        UC    U  C            UAGAUG 
                   CC UG CCUCGGGG  CAGU UU CCAGGAAUCCCU      \
                   GG AC GGAGUUCU  GUCA AA GGUCCUUAGGGG      C
GCGACCCGGUCGACACUUU^ U  U        U-    U  A            UAGAAU 
.       110       100        90         80        70
Deep sequencing
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CommentThere is a second Dicer cut -2 on both arms. Although there is a templated T at the 3' end of the 3p arm, this transcript is annotated as a Group 2 miRNA given the CAGE data in human and the 5' starting cut of 3' offset reads in various vertebrate taxa.
3' NTU Yes
MotifsCNNC at 3p(+17)
Tissue expression
 +
He Ki Te To Wh
Mature sequence

Ocu-Mir-145_5p

mirBase accessionMIMAT0048251
Sequence
0- GUCCAGUUUUCCCAGGAAUCCCU -23
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Star sequence

Ocu-Mir-145_3p*

mirBase accessionMIMAT0048252
Sequence
38- GGAUUCCUGGAAAUACUGUUCU -60
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