MirGeneDB 3.0
MirGeneDB ID

Hsa-Mir-145

Family name MIR-145 (all species)
Seed UCCAGUU
Species Human (Homo sapiens)
MiRBase ID hsa-mir-145
Paralogues
Orthologues Aca-Mir-145  Ami-Mir-145  Bta-Mir-145  Cfa-Mir-145  Cja-Mir-145  Cli-Mir-145  Cmi-Mir-145  Cpi-Mir-145  Cpo-Mir-145  Dno-Mir-145  Dre-Mir-145  Ebu-Mir-145  Eca-Mir-145  Ete-Mir-145  Gga-Mir-145  Gja-Mir-145  Gmo-Mir-145  Laf-Mir-145  Lch-Mir-145  Loc-Mir-145  Mal-Mir-145  Mdo-Mir-145  Mml-Mir-145  Mmr-Mir-145  Mmu-Mir-145  Mun-Mir-145  Neu-Mir-145  Oan-Mir-145  Ocu-Mir-145  Pab-Mir-145  Pbv-Mir-145  Pma-Mir-145  Rno-Mir-145  Sha-Mir-145  Spt-Mir-145  Sto-Mir-145  Tgu-Mir-145  Xla-Mir-145-P1  Xla-Mir-145-P2  Xtr-Mir-145 
Node of Origin (locus) Vertebrata
Node of Origin (family) Vertebrata
Genome context
(hg38)		 chr5: 149430661-149430720 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-145)		 Mir-143 chr5: 149428944-149428998 [+] UCSC Ensembl
Mir-145 chr5: 149430661-149430720 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
AAGGCCACUCGCUCCCACCUUGUCCUCACGGUCCAGUUUUCCCAGGAAUCCCUUAGAUGCUAAGAUGGGGAUUCCUGGAAAUACUGUUCUUGAGGUCAUGGUUUCACAGCUGGAUUUGCC
Get precursor sequence
Structure
        10          20        30        40        50          
AAGGCCACUCGCUCCCA--| U  U     C  UC    U  C            UAGAUG 
                   CC UG CCUCA GG  CAGU UU CCAGGAAUCCCU      \
                   GG AC GGAGU UC  GUCA AA GGUCCUUAGGGG      C
CCGUUUAGGUCGACACUUU^ U  U     -  UU    U  A            UAGAAU 
.       110       100         90        80        70
Deep sequencing
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CommentThere is a second Dicer cut -2 on both arms. Although there is a templated T at the 3' end of the 3p arm, the post-transcriptional addition of a terminal 3' U is supported by the CAGE data from de Rie et al. (2017).
3' NTU Yes
MotifsCNNC at 3p(+17)
Tissue expression
-   +
Dc Dc Dr Dr Xp Xp Bl Br Br Ce Ce Co Fo He Ki Le Li Li Lu Pa Pl Pl Sk Sk Sk Sm Sp Sp St Te Th Ut
Mature sequence

Hsa-Mir-145_5p
mirBase accessionMIMAT0000437
Sequence 
0- GUCCAGUUUUCCCAGGAAUCCCU -23
Get sequence
Proposed targets microrna.org: MIMAT0000437
TargetScanVert: hsa-miR-145-5p
TargetMiner: hsa-miR-145-5p
miRDB: MIMAT0000437
Star sequence

Hsa-Mir-145_3p*
mirBase accessionMIMAT0004601
Sequence 
38- GGAUUCCUGGAAAUACUGUUCU -60
Get sequence
Proposed targets microrna.org: MIMAT0004601
TargetScanVert: hsa-miR-145-3p
TargetMiner: hsa-miR-145-3p
miRDB: MIMAT0004601