Mir-22-P2c

MirGeneDB ID

Bfl-Mir-22-P2c

Family name

MIR-22 (all species)

Seed

CAGCUCC

Species

Florida lancelet (Branchiostoma floridae)

MiRBase ID

bfl-mir-4868c

Paralogues

Bfl-Mir-22-o3d Bfl-Mir-22-o3e Bfl-Mir-22-P1 Bfl-Mir-22-P2a Bfl-Mir-22-P2b

Orthologues

Aae-Mir-22-P2 Aga-Mir-22-P2 Agr-Mir-22-P2 Asu-Mir-22-P2 Bge-Mir-22-P2 Bla-Mir-22-P2c Cbr-Mir-22-P2-v1 Cbr-Mir-22-P2-v2 Cel-Mir-22-P2 Csc-Mir-22-P2 Cte-Mir-22-P2 Dan-Mir-22-P2 Dlo-Mir-22-P2 Dma-Mir-22-P2 Dme-Mir-22-P2 Dmo-Mir-22-P2 Dpu-Mir-22-P2 Dsi-Mir-22-P2 Dya-Mir-22-P2 Eba-Mir-22-P2 Esc-Mir-22-P2 Gpa-Mir-22-P2 Hme-Mir-22-P2 Hru-Mir-22-P2 Isc-Mir-22-P2 Lan-Mir-22-P2 Lgi-Mir-22-P2 Lhy-Mir-22-P2 Llo-Mir-22-P2 Mgi-Mir-22-P2 Mom-Mir-22-P2 Npo-Mir-22-P2 Ovu-Mir-22-P2 Pau-Mir-22-P2 Pca-Mir-22-P2 Pdu-Mir-22-P2 Pfl-Mir-22-P2 Pmi-Mir-22-P2 Pve-Mir-22-P2 Rph-Mir-22-P2 Sko-Mir-22-P2 Snu-Mir-22-P2 Spu-Mir-22-P2 Tca-Mir-22-P2-v1 Tca-Mir-22-P2-v2 Tur-Mir-22-P2 War-Mir-22-P2

Node of Origin (locus)

Branchiostoma

Node of Origin (family)

Bilateria

Genome context
(GCF_000003815.2_Bfl_VNyyK_genomic)

NC_049994.1: 9332985-9333043 [+] UCSC

Precursor
(pre-Mir +30nt flank)

UGCUGAUGAUGUGUACUGCUCAUGUCAGUACUGGUGAGUCUGGAUGCUGAUGAUAUGUUAGUUCCCAUCAGCUCCAAGGCUGAUCAGUAGUGAUGUGAGAUCUACUCGACGUUGUAUUC

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Structure

        10          20        30        40         50         
UGCUGAUGAUGUGUACUG--         G       G    -|   U       AUAUGU 
                    CUCAUGUCA UACUGGU AGUC UGGA GCUGAUG      \
                    GAGUGUAGU AUGACUA UCGG ACCU CGACUAC      U
CUUAUGUUGCAGCUCAUCUA         G       G    A^   -       CCUUGA 
       110       100        90        80         70        60

Deep sequencing

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Comment

It is unclear if this paralogue group represents the ancestral Mir-22-P2 gene that is seed shifted or a new paralogue derived from the ancestral P1 gene. It is also unclear if this gene is orthologous to the Mir-22-o2 gene in ambulacrarians.

3' NTU

Motifs

UG at 5p(-14), CNNC at 3p(+17)

Tissue expression

To

Star sequence

Bfl-Mir-22-P2c_5p*

mirBase accession

MIMAT0020106

Sequence

0- CUGGUGAGUCUGGAUGCUGAUG -22

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Mature sequence

Bfl-Mir-22-P2c_3p

mirBase accession

MIMAT0020107

Sequence

37- UCAGCUCCAAGGCUGAUCAGUA -59

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