MirGeneDB 3.0

MirGeneDB ID

Bfl-Mir-22-P2a

Family name MIR-22 (all species)
Seed CAGCUCC
Species Florida lancelet (Branchiostoma floridae)
MiRBase ID bfl-mir-4868a
Paralogues Bfl-Mir-22-o3d  Bfl-Mir-22-o3e  Bfl-Mir-22-P1  Bfl-Mir-22-P2b  Bfl-Mir-22-P2c 
Orthologues Aae-Mir-22-P2  Aga-Mir-22-P2  Agr-Mir-22-P2  Asu-Mir-22-P2  Bge-Mir-22-P2  Bla-Mir-22-P2a  Cbr-Mir-22-P2-v1  Cbr-Mir-22-P2-v2  Cel-Mir-22-P2  Csc-Mir-22-P2  Cte-Mir-22-P2  Dan-Mir-22-P2  Dlo-Mir-22-P2  Dma-Mir-22-P2  Dme-Mir-22-P2  Dmo-Mir-22-P2  Dpu-Mir-22-P2  Dsi-Mir-22-P2  Dya-Mir-22-P2  Eba-Mir-22-P2  Esc-Mir-22-P2  Gpa-Mir-22-P2  Hme-Mir-22-P2  Hru-Mir-22-P2  Isc-Mir-22-P2  Lan-Mir-22-P2  Lgi-Mir-22-P2  Lhy-Mir-22-P2  Llo-Mir-22-P2  Mgi-Mir-22-P2  Mom-Mir-22-P2  Npo-Mir-22-P2  Ovu-Mir-22-P2  Pau-Mir-22-P2  Pca-Mir-22-P2  Pdu-Mir-22-P2  Pfl-Mir-22-P2  Pmi-Mir-22-P2  Pve-Mir-22-P2  Rph-Mir-22-P2  Sko-Mir-22-P2  Snu-Mir-22-P2  Spu-Mir-22-P2  Tca-Mir-22-P2-v1  Tca-Mir-22-P2-v2  Tur-Mir-22-P2  War-Mir-22-P2 
Node of Origin (locus) Branchiostoma
Node of Origin (family) Bilateria
Genome context
(GCF_000003815.2_Bfl_VNyyK_genomic)
NC_049981.1: 9953158-9953217 [-] UCSC
Clustered miRNAs
(< 50kb from Mir-22-P2a)
Mir-22-P2b NC_049981.1: 9942475-9942534 [-] UCSC
Mir-4868-P2 NC_049981.1: 9942475-9942534 [-] UCSC
Mir-22-P2a NC_049981.1: 9953158-9953217 [-] UCSC
Mir-4868-P1 NC_049981.1: 9953158-9953217 [-] UCSC
Precursor
(pre-Mir +30nt flank)
AGAUUGAGAAAUGAUGUGGUCUUCUCGCCCCUGAUCAGCCCGGAAGCUGUUACGUCACUUCCGUUGUAUCAGCUCCAGCGCUGAUCAGUGACGCGGUGACUUAAAAACAACUACGCCAGG
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Structure
        10          20        30          40         50         
AGAUUGAGAAAUGAUGU--    UU U   CC--         CC-|  A    U  CGUCAC 
                   GGUC  C CGC    CUGAUCAGC   GGA GCUG UA      U
                   UCAG  G GCG    GACUAGUCG   CCU CGAC AU      U
GGACCGCAUCAACAAAAAU    U- -   CAGU         CGA^  -    U  GUUGCC 
.       110       100          90        80         70        60
Deep sequencing
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CommentIt is unclear if this paralogue group represents the ancestral Mir-22-P2 gene that is seed shifted or a new paralogue derived from the ancestral P1 gene. It is also unclear if this gene is orthologous to the Mir-22-o2 gene in ambulacrarians.
3' NTU Yes
MotifsUG at 5p(-14), CNNC at 3p(+17)
Tissue expression
 +
To
Star sequence

Bfl-Mir-22-P2a_5p* (predicted)

mirBase accessionNone
Sequence
0- CUGAUCAGCCCGGAAGCUGUUA -22
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Mature sequence

Bfl-Mir-22-P2a_3p

mirBase accessionMIMAT0020104
Sequence
38- UCAGCUCCAGCGCUGAUCAGUG -60
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