Mir-19-P1a2

MirGeneDB ID

Gmo-Mir-19-P1a2

Family name

MIR-19 (all species)

Seed

GUGCAAA

Species

Cod (Gadus morhua)

MiRBase ID

gmo-mir-19a-2

Paralogues

Gmo-Mir-19-P1a1 Gmo-Mir-19-P2a1 Gmo-Mir-19-P2a2 Gmo-Mir-19-P2c Gmo-Mir-19-P2d

Orthologues

Aca-Mir-19-P1a Ami-Mir-19-P1a Bta-Mir-19-P1a Cfa-Mir-19-P1a Cja-Mir-19-P1a Cli-Mir-19-P1a Cmi-Mir-19-P1a-v1 Cmi-Mir-19-P1a-v2 Cpi-Mir-19-P1a Cpo-Mir-19-P1a Dno-Mir-19-P1a Dre-Mir-19-P1a2 Eca-Mir-19-P1a Ete-Mir-19-P1a Gga-Mir-19-P1a Gja-Mir-19-P1a Hsa-Mir-19-P1a Laf-Mir-19-P1a Lch-Mir-19-P1a Loc-Mir-19-P1a Mal-Mir-19-P1a2 Mdo-Mir-19-P1a Mml-Mir-19-P1a Mmr-Mir-19-P1a Mmu-Mir-19-P1a Mun-Mir-19-P1a Neu-Mir-19-P1a Oan-Mir-19-P1a Ocu-Mir-19-P1a Pab-Mir-19-P1a Pbv-Mir-19-P1a Rno-Mir-19-P1a Sha-Mir-19-P1a Spt-Mir-19-P1a Sto-Mir-19-P1a-v1 Sto-Mir-19-P1a-v2 Tgu-Mir-19-P1a Tni-Mir-19-P1a2 Xtr-Mir-19-P1a

Node of Origin (locus)

Clupeocephala

Node of Origin (family)

Vertebrata

Genome context
(Gadus_morhua.gadMor1.dna.toplevel)

GeneScaffold_918: 373145-373201 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-19-P1a2)

Mir-17-P1a2 GeneScaffold_918: 372883-372941 [+] UCSC Ensembl
Mir-17-P2a2 GeneScaffold_918: 373010-373074 [+] UCSC Ensembl
Mir-19-P1a2 GeneScaffold_918: 373145-373201 [+] UCSC Ensembl
Mir-17-P4a2 GeneScaffold_918: 373326-373385 [+] UCSC Ensembl
Mir-19-P2a2 GeneScaffold_918: 373455-373516 [+] UCSC Ensembl
Mir-92-P1a2 GeneScaffold_918: 373563-373620 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

GUCUUCGGUGGUCUAAAACGGUUCACUGCCAGUUUUGCGUAGUUGCUCUGCAAGAAAAUUGAGUUGUGCAAAUCUAUGCAAAACUGACGGUGUACUGUGUCUCUGCAAAAUCAAGGG

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Structure

        10          20        30        40          50       
GUCUUCGGUGGUCUAAA--     U     C             --|   UCU  AAGAA 
                   ACGGU CACUG CAGUUUUGCGUAG  UUGC   GC     \
                   UGUCA GUGGC GUCAAAACGUAUC  AACG   UG     A
GGGAACUAAAACGUCUCUG     U     A             UA^   UGU  AGUUA 
     110       100        90        80        70        60

Deep sequencing

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Comment

There is a second Drosha cut -2 on the 5p arm.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Br	Gi	He	In	Li	Sk	Sp	Wh

Star sequence

Gmo-Mir-19-P1a2_5p*

mirBase accession

MIMAT0044322

Sequence

0- AGUUUUGCGUAGUUGCUCUGC -21

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Mature sequence

Gmo-Mir-19-P1a2_3p

mirBase accession

MIMAT0044303

Sequence

34- UGUGCAAAUCUAUGCAAAACUGA -57

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