MirGeneDB 3.0

MirGeneDB ID

Hsa-Mir-146-P1

Family name MIR-146 (all species)
Seed GAGAACU
Species Human (Homo sapiens)
MiRBase ID hsa-mir-146b
Paralogues Hsa-Mir-146-P4 
Orthologues Aca-Mir-146-P1  Ami-Mir-146-P1  Bta-Mir-146-P1  Cfa-Mir-146-P1  Cja-Mir-146-P1  Cli-Mir-146-P1  Cmi-Mir-146-P1  Cpi-Mir-146-P1  Cpo-Mir-146-P1  Dno-Mir-146-P1  Dre-Mir-146-P1  Ebu-Mir-146  Eca-Mir-146-P1  Ete-Mir-146-P1  Gga-Mir-146-P1  Gja-Mir-146-P1  Gmo-Mir-146-P1  Laf-Mir-146-P1  Lch-Mir-146-P1  Loc-Mir-146-P1  Mal-Mir-146-P1  Mdo-Mir-146-P1  Mml-Mir-146-P1  Mmr-Mir-146-P1  Mmu-Mir-146-P1  Mun-Mir-146-P1  Oan-Mir-146-P1  Ocu-Mir-146-P1  Pab-Mir-146-P1  Pbv-Mir-146-P1  Pma-Mir-146  Rno-Mir-146-P1  Sha-Mir-146-P1  Spt-Mir-146-P1  Tgu-Mir-146-P1  Tni-Mir-146-P1 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Vertebrata
Genome context
(hg38)
chr10: 102436520-102436578 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
CAGGCUGAAAGAACUUUGGCCACCUGGCACUGAGAACUGAAUUCCAUAGGCUGUGAGCUCUAGCAAUGCCCUGUGGACUCAGUUCUGGUGCCCGGCAGUGCUACAACAUCAAUGCCAAG
Get precursor sequence
Structure
        10             20        30        40        50          
CAGGCUGAAAGAACUUUG-----|  ACCU      G        AU        CU  GAGCU 
                       GCC    GGCACU AGAACUGA  UCCAUAGG  GU     \
                       CGG    CCGUGG UCUUGACU  AGGUGUCC  UA     C
GAACCGUAACUACAACAUCGUGA^  C---      -        C-        CG  ACGAU 
       110       100           90         80         70
Deep sequencing
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CommentThere is a second Dicer cut -1 on the 3p arm.
3' NTU No
MotifsUG at 5p(-14), CNNC at 3p(+17)
Tissue expression
 +
Dc Dc Dr Dr Xp Xp Bl Br Br Ce Ce Co Fo He Ki Le Li Li Lu Pa Pl Pl Sk Sk Sk Sm Sp Sp St Te Th Ut
Mature sequence

Hsa-Mir-146-P1_5p

mirBase accessionMIMAT0002809
Sequence
0- UGAGAACUGAAUUCCAUAGGCUGU -24
Get sequence
Proposed targets microrna.org: MIMAT0002809
TargetScanVert: hsa-miR-146b-5p
TargetMiner: hsa-miR-146b-5p
miRDB: MIMAT0002809
Star sequence

Hsa-Mir-146-P1_3p*

mirBase accessionMIMAT0004766
Sequence
37- GCCCUGUGGACUCAGUUCUGGU -59
Get sequence
Proposed targets microrna.org: MIMAT0004766
TargetScanVert: hsa-miR-146b-3p
TargetMiner: hsa-miR-146b-3p
miRDB: MIMAT0004766