MirGeneDB 3.0

MirGeneDB ID

Dre-Mir-221-P2a1

Family name MIR-221 (all species)
Seed GCUACAU
Species Zebrafish (Danio rerio)
MiRBase ID dre-mir-221
Paralogues Dre-Mir-221-P1a1  Dre-Mir-221-P1c  Dre-Mir-221-P2a2 
Orthologues Aca-Mir-221-P2a  Ami-Mir-221-P2a  Bta-Mir-221-P2a  Cfa-Mir-221-P2a  Cja-Mir-221-P2a  Cli-Mir-221-P2a  Cmi-Mir-221-P2a  Cpi-Mir-221-P2a  Cpo-Mir-221-P2a  Dno-Mir-221-P2a  Eca-Mir-221-P2a  Ete-Mir-221-P2a  Gga-Mir-221-P2a  Gja-Mir-221-P2a  Gmo-Mir-221-P2a1  Hsa-Mir-221-P2a  Laf-Mir-221-P2a  Lch-Mir-221-P2a  Loc-Mir-221-P2a  Mal-Mir-221-P2a1  Mdo-Mir-221-P2a  Mml-Mir-221-P2a  Mmr-Mir-221-P2a  Mmu-Mir-221-P2a  Mun-Mir-221-P2a  Neu-Mir-221-P2a  Oan-Mir-221-P2a  Ocu-Mir-221-P2a  Pab-Mir-221-P2a  Pbv-Mir-221-P2a  Rno-Mir-221-P2a  Sha-Mir-221-P2a  Spt-Mir-221-P2a  Sto-Mir-221-P2a  Tgu-Mir-221-P2a  Tni-Mir-221-P2a1  Xtr-Mir-221-P2a 
Node of Origin (locus) Clupeocephala
Node of Origin (family) Vertebrata
Genome context
(danRer11)
chr9: 33920955-33921017 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-221-P2a1)
Mir-221-P2a1 chr9: 33920955-33921017 [-] UCSC Ensembl
Mir-221-P1a1 chr9: 33921481-33921542 [-] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
CGAAGGAUGAAGUCUUUUGUGCUGUCGUGAACCUGGCAUACAAUGUAGAUUUCUGUGUGGUACUAUCUACAGCUACAUUGUCUGCUGGGUUUCAGGCCAGCAGAAUAAUUCUGCUCUACUGAC
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Structure
        10          20         30        40        50        60  
CGAAGGAUGAAGUCUUU-- G    -|  GU     UG   U         AUUU    GUGGU 
                   U UGCU GUC  GAACC  GCA ACAAUGUAG    CUGU     A
                   A ACGA CGG  UUUGG  CGU UGUUACAUC    GACA     C
CAGUCAUCUCGUCUUAAUA G    C^  AC     GU   C         ----    UCUAU 
 120       110       100        90        80            70
Deep sequencing
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3' NTU No
MotifsCNNC at 3p(+17), UGUG in loop
Tissue expression
 +
Br Br Em Ey Gu Gu He Li Li Ov Te
Star sequence

Dre-Mir-221-P2a1_5p*

mirBase accessionMIMAT0031926
Sequence
0- ACCUGGCAUACAAUGUAGAUUUCUGU -26
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Mature sequence

Dre-Mir-221-P2a1_3p

mirBase accessionMIMAT0001288
Sequence
40- AGCUACAUUGUCUGCUGGGUUUC -63
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Proposed targets TargetScanFish: dre-miR-221