MirGeneDB 3.0

MirGeneDB ID

Hsa-Mir-221-P1a

Family name MIR-221 (all species)
Seed GCUACAU
Species Human (Homo sapiens)
MiRBase ID hsa-mir-222
Paralogues Hsa-Mir-221-P2a 
Orthologues Aca-Mir-221-P1a  Ami-Mir-221-P1a  Bta-Mir-221-P1a  Cfa-Mir-221-P1a  Cja-Mir-221-P1a1  Cja-Mir-221-P1a2  Cli-Mir-221-P1a  Cmi-Mir-221-P1a  Cpi-Mir-221-P1a  Cpo-Mir-221-P1a  Dno-Mir-221-P1a  Dre-Mir-221-P1a1  Eca-Mir-221-P1a  Ete-Mir-221-P1a  Gga-Mir-221-P1a  Gja-Mir-221-P1a  Gmo-Mir-221-P1a1  Gmo-Mir-221-P1a2  Laf-Mir-221-P1a  Lch-Mir-221-P1a  Loc-Mir-221-P1a  Mal-Mir-221-P1a1  Mal-Mir-221-P1a2  Mdo-Mir-221-P1a  Mml-Mir-221-P1a  Mmr-Mir-221-P1a  Mmu-Mir-221-P1a  Mun-Mir-221-P1a  Neu-Mir-221-P1a  Oan-Mir-221-P1a  Ocu-Mir-221-P1a  Pab-Mir-221-P1a  Pbv-Mir-221-P1a  Rno-Mir-221-P1a  Sha-Mir-221-P1a  Spt-Mir-221-P1a  Sto-Mir-221-P1a  Tgu-Mir-221-P1a  Tni-Mir-221-P1a1  Xla-Mir-221-P1a3  Xla-Mir-221-P1a4  Xtr-Mir-221-P1a 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Vertebrata
Genome context
(hg38)
chrX: 45747033-45747096 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-221-P1a)
Mir-221-P2a chrX: 45746180-45746242 [-] UCSC Ensembl
Mir-221-P1a chrX: 45747033-45747096 [-] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
CAGCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCUUCUGCUUCAGUG
Get precursor sequence
Structure
        10          20        30        40         50        60 
CAGCUGCUGGAAGGUGU--    A  C   AU              -|    AUCCUGUCUUU 
                   AGGU CC UCA  GGCUCAGUAGCCAG UGUAG           \
                   UCUA GG AGU  CUGGGUCAUCGGUC ACAUC           C
GUGACUUCGUCUUCGAUCU    C  U   CU              U^    GACGACUAAUG 
  120       110       100        90        80        70
Deep sequencing
Go to detailed chart
3' NTU Yes
MotifsCNNC at 3p(+17), UGUG in loop
Tissue expression
 +
Dc Dc Dr Dr Xp Xp Bl Br Br Ce Ce Co Fo He Ki Le Li Li Lu Pa Pl Pl Sk Sk Sk Sm Sp Sp St Te Th Ut
Star sequence

Hsa-Mir-221-P1a_5p*

mirBase accessionMIMAT0004569
Sequence
0- GGCUCAGUAGCCAGUGUAGAUCC -23
Get sequence
Proposed targets microrna.org: MIMAT0004569
TargetScanVert: hsa-miR-222-5p
TargetMiner: hsa-miR-222-5p
miRDB: MIMAT0004569
Mature sequence

Hsa-Mir-221-P1a_3p

mirBase accessionMIMAT0000279
Sequence
40- AGCUACAUCUGGCUACUGGGUCUC -64
Get sequence
Proposed targets microrna.org: MIMAT0000279
TargetScanVert: hsa-miR-222-3p
TargetMiner: hsa-miR-222-3p
miRDB: MIMAT0000279