Mir-181-P2b

MirGeneDB ID

Hsa-Mir-181-P2b

Family name

MIR-181 (all species)

Seed

ACAUUCA

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-181b-2

Paralogues

Hsa-Mir-181-P1a Hsa-Mir-181-P1b Hsa-Mir-181-P1c Hsa-Mir-181-P2a Hsa-Mir-181-P2c

Orthologues

Aca-Mir-181-P2b Ami-Mir-181-P2b Bta-Mir-181-P2b Cfa-Mir-181-P2b Cja-Mir-181-P2b Cli-Mir-181-P2b Cmi-Mir-181-P2b Cpi-Mir-181-P2b Cpo-Mir-181-P2b Dno-Mir-181-P2b Dre-Mir-181-P2b2 Eca-Mir-181-P2b Ete-Mir-181-P2b Gga-Mir-181-P2b Gja-Mir-181-P2b Gmo-Mir-181-P2b2 Laf-Mir-181-P2b Lch-Mir-181-P2b Loc-Mir-181-P2b Mal-Mir-181-P2b2 Mdo-Mir-181-P2b Mml-Mir-181-P2b Mmr-Mir-181-P2b Mmu-Mir-181-P2b Mun-Mir-181-P2b Neu-Mir-181-P2b Oan-Mir-181-P2b Ocu-Mir-181-P2b Pab-Mir-181-P2b Pbv-Mir-181-P2b Rno-Mir-181-P2b Sha-Mir-181-P2b Spt-Mir-181-P2b Sto-Mir-181-P2b Tgu-Mir-181-P2b Tni-Mir-181-P2b1 Xla-Mir-181-P2b3 Xla-Mir-181-P2b4 Xtr-Mir-181-P2b

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Vertebrata

Genome context
(hg38)

chr9: 124693725-124693784 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-181-P2b)

Mir-181-P1b chr9: 124692480-124692539 [+] UCSC Ensembl
Mir-181-P2b chr9: 124693725-124693784 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

CACCAACUGAAAACACUGAUGGCUGCACUCAACAUUCAUUGCUGUCGGUGGGUUUGAGUCUGAAUCAACUCACUGAUCAAUGAAUGCAAACUGCGGACCAAACAACCCAAAGGAAGCAAA

Get precursor sequence

Structure

        10         20         30        40        50        60
CACCAACUGAAAACACUGA-   -|    CUCAA         CU           UGAGU 
                    UGG CUGCA     CAUUCAUUG  GUCGGUGGGUU     C
                    ACC GGCGU     GUAAGUAAC  UAGUCACUCAA     U
AAACGAAGGAAACCCAACAA   A^    CAAAC         --           CUAAG 
.       110       100        90        80          70

Deep sequencing

Go to detailed chart

Comment

There is a second Dicer cut +1 on both arms.

3' NTU

Motifs

UG at 5p(-14)

Tissue expression

Dc	Dc	Dr	Dr	Xp	Xp	Bl	Br	Br	Ce	Ce	Co	Fo	He	Ki	Le	Li	Li	Lu	Pa	Pl	Pl	Sk	Sk	Sk	Sm	Sp	Sp	St	Te	Th	Ut

Mature sequence

Hsa-Mir-181-P2b_5p

mirBase accession

MIMAT0000257

Sequence

0- AACAUUCAUUGCUGUCGGUGGGUU -24

Get sequence

Proposed targets

microrna.org: MIMAT0000257
TargetScanVert: hsa-miR-181b-5p
TargetMiner: hsa-miR-181b-5p
miRDB: MIMAT0000257

Star sequence

Hsa-Mir-181-P2b_3p*

mirBase accession

MIMAT0031893

Sequence

38- CUCACUGAUCAAUGAAUGCAAA -60

Get sequence

Proposed targets

TargetScanVert: hsa-miR-181b-2-3p
miRDB: MIMAT0031893