MirGeneDB 2.1
MirGeneDB ID

Hsa-Mir-181-P2b

Family name MIR-181 (all species)
Seed ACAUUCA
Species Human (Homo sapiens)
MiRBase ID hsa-mir-181b-2
Paralogues Hsa-Mir-181-P1a  Hsa-Mir-181-P1b  Hsa-Mir-181-P1c  Hsa-Mir-181-P2a  Hsa-Mir-181-P2c 
Orthologues Aca-Mir-181-P2b  Ami-Mir-181-P2b  Bta-Mir-181-P2b  Cfa-Mir-181-P2b  Cli-Mir-181-P2b  Cmi-Mir-181-P2b  Cpi-Mir-181-P2b  Cpo-Mir-181-P2b  Dno-Mir-181-P2b  Dre-Mir-181-P2b2  Ete-Mir-181-P2b  Gga-Mir-181-P2b  Gja-Mir-181-P2b  Gmo-Mir-181-P2b2  Lch-Mir-181-P2b  Loc-Mir-181-P2b  Mal-Mir-181-P2b2  Mdo-Mir-181-P2b  Mml-Mir-181-P2b  Mmu-Mir-181-P2b  Mun-Mir-181-P2b  Oan-Mir-181-P2b  Ocu-Mir-181-P2b  Pbv-Mir-181-P2b  Rno-Mir-181-P2b  Sha-Mir-181-P2b  Spt-Mir-181-P2b  Sto-Mir-181-P2b  Tgu-Mir-181-P2b  Tni-Mir-181-P2b1  Xla-Mir-181-P2b3  Xla-Mir-181-P2b4  Xtr-Mir-181-P2b 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Vertebrata
Genome context
(hg38)		 chr9: 124693725-124693784 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-181-P2b)		 Mir-181-P1b chr9: 124692480-124692539 [+] UCSC Ensembl
Mir-181-P2b chr9: 124693725-124693784 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
CACCAACUGAAAACACUGAUGGCUGCACUCAACAUUCAUUGCUGUCGGUGGGUUUGAGUCUGAAUCAACUCACUGAUCAAUGAAUGCAAACUGCGGACCAAACAACCCAAAGGAAGCAAA
Get precursor sequence
Structure
        10         20         30        40        50        60
CACCAACUGAAAACACUGA-   -|    CUCAA         CU           UGAGU 
                    UGG CUGCA     CAUUCAUUG  GUCGGUGGGUU     C
                    ACC GGCGU     GUAAGUAAC  UAGUCACUCAA     U
AAACGAAGGAAACCCAACAA   A^    CAAAC         --           CUAAG 
.       110       100        90        80          70
Deep sequencing
Go to detailed chart
CommentThere is a second Dicer cut +1 on both arms.
3' NTU No
MotifsUG at 5p(-14)
Tissue expression
-   +
1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 3- 3- 3- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 5- 5- 5- 5- 5- 5- 5- 6- 6- 6- 6- 6-
Mature sequence

Hsa-Mir-181-P2b_5p
mirBase accessionMIMAT0000257
Sequence 
0- AACAUUCAUUGCUGUCGGUGGGUU -24
Get sequence
Proposed targets microrna.org: MIMAT0000257
TargetScanVert: hsa-miR-181b-5p
TargetMiner: hsa-miR-181b-5p
miRDB: MIMAT0000257
Star sequence

Hsa-Mir-181-P2b_3p*
mirBase accessionMIMAT0031893
Sequence 
38- CUCACUGAUCAAUGAAUGCAAA -60
Get sequence
Proposed targets TargetScanVert: hsa-miR-181b-2-3p
miRDB: MIMAT0031893