Mir-17-P1a

MirGeneDB ID

Aca-Mir-17-P1a

Family name

MIR-17 (all species)

Seed

AAAGUGC

Species

Green anole lizard (Anolis carolinensis)

MiRBase ID

aca-mir-17

Paralogues

Aca-Mir-17-P1c Aca-Mir-17-P2a Aca-Mir-17-P2c Aca-Mir-17-P4a Aca-Mir-17-P4c

Orthologues

Ami-Mir-17-P1a Bta-Mir-17-P1a Cfa-Mir-17-P1a Cja-Mir-17-P1a Cli-Mir-17-P1a Cmi-Mir-17-P1a Cpi-Mir-17-P1a Cpo-Mir-17-P1a Dno-Mir-17-P1a Dre-Mir-17-P1a1 Dre-Mir-17-P1a2 Eca-Mir-17-P1a Ete-Mir-17-P1a Gga-Mir-17-P1a Gja-Mir-17-P1a Gmo-Mir-17-P1a1 Gmo-Mir-17-P1a2 Hsa-Mir-17-P1a Laf-Mir-17-P1a Lch-Mir-17-P1a Loc-Mir-17-P1a Mal-Mir-17-P1a1 Mal-Mir-17-P1a2 Mdo-Mir-17-P1a Mml-Mir-17-P1a Mmr-Mir-17-P1a Mmu-Mir-17-P1a Mun-Mir-17-P1a Neu-Mir-17-P1a Oan-Mir-17-P1a Ocu-Mir-17-P1a Pab-Mir-17-P1a Pbv-Mir-17-P1a Rno-Mir-17-P1a Sha-Mir-17-P1a Spt-Mir-17-P1a Sto-Mir-17-P1a Tgu-Mir-17-P1a Tni-Mir-17-P1a1 Tni-Mir-17-P1a2 Xla-Mir-17-P1a3 Xla-Mir-17-P1a4 Xtr-Mir-17-P1a

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Vertebrata

Genome context
(anoCar2)

GL343584.1: 108268-108328 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-17-P1a)

Mir-17-P1a GL343584.1: 108268-108328 [+] UCSC Ensembl
Mir-19-P1a GL343584.1: 108539-108596 [+] UCSC Ensembl
Mir-17-P4a GL343584.1: 108699-108757 [+] UCSC Ensembl
Mir-19-P2a GL343584.1: 108837-108897 [+] UCSC Ensembl
Mir-92-P1a GL343584.1: 108950-109010 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

ACGAAGAUUUAAUUCAUGUCAGAGUAAUGUCAAAGUGCUUACAGUGCAGGUAGUGAUAAGUAGAACCUACUGCAGUGAAGGCACUUGUAGCAUUAUGCUGGCAACUGCCUCAAAAGGUUUG

Get precursor sequence

Structure

        10          20        30         40        50          
ACGAAGAUUUAAUUCAU--     A       CA-|       A  G     G   UGAUAA 
                   GUCAG GUAAUGU   AAGUGCUU CA UGCAG UAG      \
                   CGGUC UAUUACG   UUCACGGA GU ACGUC AUC      G
GUUUGGAAAACUCCGUCAA     G       AUG^       A  G     -   CAAGAU 
 .       110       100        90        80        70

Deep sequencing

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Comment

There is a second Dicer cut -1 on the 3p arm, which is a Group 2 miRNA isomir.

3' NTU

Motifs

UG at 5p(-14), CNNC at 3p(+17)

Tissue expression

Sk	Ta	Ta	To	Wh

Mature sequence

Aca-Mir-17-P1a_5p

mirBase accession

MIMAT0021803

Sequence

0- CAAAGUGCUUACAGUGCAGGUAG -23

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Star sequence

Aca-Mir-17-P1a_3p*

mirBase accession

MIMAT0021804

Sequence

38- ACUGCAGUGAAGGCACUUGUAGC -61

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