Mir-19-P2a

MirGeneDB ID

Hsa-Mir-19-P2a

Family name

MIR-19 (all species)

Seed

GUGCAAA

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-19b-1

Paralogues

Hsa-Mir-19-P1a Hsa-Mir-19-P2c

Orthologues

Aca-Mir-19-P2a Ami-Mir-19-P2a Bta-Mir-19-P2a Cfa-Mir-19-P2a Cja-Mir-19-P2a Cli-Mir-19-P2a Cmi-Mir-19-P2a Cpi-Mir-19-P2a Cpo-Mir-19-P2a Dno-Mir-19-P2a Dre-Mir-19-P2a1 Dre-Mir-19-P2a2 Eca-Mir-19-P2a Ete-Mir-19-P2a Gga-Mir-19-P2a Gja-Mir-19-P2a Gmo-Mir-19-P2a1 Gmo-Mir-19-P2a2 Laf-Mir-19-P2a Lch-Mir-19-P2a Loc-Mir-19-P2a Mal-Mir-19-P2a1 Mal-Mir-19-P2a2 Mdo-Mir-19-P2a Mml-Mir-19-P2a Mmr-Mir-19-P2a Mmu-Mir-19-P2a Mun-Mir-19-P2a Oan-Mir-19-P2a5 Oan-Mir-19-P2a6 Ocu-Mir-19-P2a Pab-Mir-19-P2a Pbv-Mir-19-P2a Rno-Mir-19-P2a Sha-Mir-19-P2a Spt-Mir-19-P2a Sto-Mir-19-P2a Tgu-Mir-19-P2a Tni-Mir-19-P2a1 Tni-Mir-19-P2a2 Xla-Mir-19-P2a3 Xla-Mir-19-P2a4 Xtr-Mir-19-P2a

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Vertebrata

Genome context
(hg38)

chr13: 91351207-91351267 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-19-P2a)

Mir-17-P1a chr13: 91350618-91350677 [+] UCSC Ensembl
Mir-17-P2a chr13: 91350756-91350820 [+] UCSC Ensembl
Mir-19-P1a chr13: 91350904-91350961 [+] UCSC Ensembl
Mir-17-P4a chr13: 91351072-91351130 [+] UCSC Ensembl
Mir-19-P2a chr13: 91351207-91351267 [+] UCSC Ensembl
Mir-92-P1a chr13: 91351324-91351382 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

UGUCCUGUUACUGAACACUGUUCUAUGGUUAGUUUUGCAGGUUUGCAUCCAGCUGUGUGAUAUUCUGCUGUGCAAAUCCAUGCAAAACUGACUGUGGUAGUGAAAAGUCUGUAGAAAAGUA

Get precursor sequence

Structure

        10            20        30         40         50          
UGUCCUGUUACUGAACA----|  UU                 -  -      UC    UGUGUG 
                     CUG  CUAUGGUUAGUUUUGCA GG UUUGCA  CAGC      \
                     GAU  GGUGUCAGUCAAAACGU CC AAACGU  GUCG      A
AUGAAAAGAUGUCUGAAAAGU^  --                 A  U      --    UCUUAU 
 .       110       100          90        80          70

Deep sequencing

Go to detailed chart

3' NTU

Motifs

UGUG in loop

Tissue expression

Dc	Dc	Dr	Dr	Xp	Xp	Bl	Br	Br	Ce	Ce	Co	Fo	He	Ki	Le	Li	Li	Lu	Pa	Pl	Pl	Sk	Sk	Sk	Sm	Sp	Sp	St	Te	Th	Ut

Star sequence

Hsa-Mir-19-P2a_5p*

mirBase accession

MIMAT0004491

Sequence

0- AGUUUUGCAGGUUUGCAUCCAGC -23

Get sequence

Proposed targets

microrna.org: MIMAT0004491
TargetScanVert: hsa-miR-19b-1-5p
TargetMiner: hsa-miR-19b-1-5p
miRDB: MIMAT0004491

Mature sequence

Hsa-Mir-19-P2a_3p

mirBase accession

MIMAT0000074

Sequence

38- UGUGCAAAUCCAUGCAAAACUGA -61

Get sequence

Proposed targets

microrna.org: MIMAT0000074
TargetScanVert: hsa-miR-19b-3p
TargetMiner: hsa-miR-19b-3p
miRDB: MIMAT0000074