MirGeneDB 2.1

MirGeneDB ID

Hsa-Mir-17-P2a

Family name MIR-17 (all species)
Seed AAGGUGC
Species Human (Homo sapiens)
MiRBase ID hsa-mir-18a
Paralogues Hsa-Mir-17-P1a  Hsa-Mir-17-P1c  Hsa-Mir-17-P1d  Hsa-Mir-17-P2c  Hsa-Mir-17-P4a  Hsa-Mir-17-P4c  Hsa-Mir-17-P4d 
Orthologues Aca-Mir-17-P2a  Ami-Mir-17-P2a  Bta-Mir-17-P2a  Cfa-Mir-17-P2a  Cli-Mir-17-P2a  Cmi-Mir-17-P2a  Cpi-Mir-17-P2a  Cpo-Mir-17-P2a  Dno-Mir-17-P2a  Dre-Mir-17-P2a1  Dre-Mir-17-P2a2  Ete-Mir-17-P2a  Gga-Mir-17-P2a  Gja-Mir-17-P2a  Gmo-Mir-17-P2a1  Gmo-Mir-17-P2a2  Lch-Mir-17-P2a  Loc-Mir-17-P2a  Mal-Mir-17-P2a2a  Mal-Mir-17-P2a2b  Mdo-Mir-17-P2a  Mml-Mir-17-P2a  Mmu-Mir-17-P2a  Mun-Mir-17-P2a  Oan-Mir-17-P2a  Ocu-Mir-17-P2a  Pbv-Mir-17-P2a  Rno-Mir-17-P2a  Sha-Mir-17-P2a  Spt-Mir-17-P2a  Sto-Mir-17-P2a  Tgu-Mir-17-P2a  Tni-Mir-17-P2a1  Tni-Mir-17-P2a2  Xla-Mir-17-P2a3  Xla-Mir-17-P2a4  Xtr-Mir-17-P2a 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Vertebrata
Genome context
(hg38)
chr13: 91350756-91350820 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-17-P2a)
Mir-17-P1a chr13: 91350618-91350677 [+] UCSC Ensembl
Mir-17-P2a chr13: 91350756-91350820 [+] UCSC Ensembl
Mir-19-P1a chr13: 91350904-91350961 [+] UCSC Ensembl
Mir-17-P4a chr13: 91351072-91351130 [+] UCSC Ensembl
Mir-19-P2a chr13: 91351207-91351267 [+] UCSC Ensembl
Mir-92-P1a chr13: 91351324-91351382 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
GGGCCUGCUGAUGUUGAGUGCUUUUUGUUCUAAGGUGCAUCUAGUGCAGAUAGUGAAGUAGAUUAGCAUCUACUGCCCUAAGUGCUCCUUCUGGCAUAAGAAGUUAUGUAUUCAUCCAAUAAUUC
Get precursor sequence
Structure
        10          20        30          40        50        60 
GGGCCUGCUGAUGUUGAGU--         U   --|  U   UC   U    A   UGAAGUA 
                     GCUUUUUGU CUA  AGG GCA  UAG GCAG UAG       G
                     UGAAGAAUA GGU  UCC CGU  AUC CGUC AUC       A
CUUAAUAACCUACUUAUGUAU         C   CU^  U   GA   C    -   UACGAUU 
   120       110       100        90        80         70
Deep sequencing
Go to detailed chart
CommentThere is a second Drosha cut -2 on the 3p arm.
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
 +
1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 3- 3- 3- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 4- 5- 5- 5- 5- 5- 5- 5- 6- 6- 6- 6- 6-
Mature sequence

Hsa-Mir-17-P2a_5p

mirBase accessionMIMAT0000072
Sequence
0- UAAGGUGCAUCUAGUGCAGAUAG -23
Get sequence
Proposed targets microrna.org: MIMAT0000072
TargetScanVert: hsa-miR-18a-5p
TargetMiner: hsa-miR-18a-5p
miRDB: MIMAT0000072
Star sequence

Hsa-Mir-17-P2a_3p*

mirBase accessionMIMAT0002891
Sequence
41- ACUGCCCUAAGUGCUCCUUCUGGC -65
Get sequence
Proposed targets microrna.org: MIMAT0002891
TargetScanVert: hsa-miR-18a-3p
TargetMiner: hsa-miR-18a-3p
miRDB: MIMAT0002891