Mir-17-P1c

MirGeneDB ID

Mmu-Mir-17-P1c

Family name

MIR-17 (all species)

Seed

AAAGUGC

Species

House mouse (Mus musculus)

MiRBase ID

mmu-mir-106a

Paralogues

Mmu-Mir-17-P1a Mmu-Mir-17-P1d Mmu-Mir-17-P2a Mmu-Mir-17-P2c Mmu-Mir-17-P4a Mmu-Mir-17-P4c Mmu-Mir-17-P4d

Orthologues

Aca-Mir-17-P1c Ami-Mir-17-P1c Bta-Mir-17-P1c Cfa-Mir-17-P1c Cli-Mir-17-P1c Cmi-Mir-17-P1c Cpi-Mir-17-P1c Cpo-Mir-17-P1c Dno-Mir-17-P1c Ete-Mir-17-P1c Gga-Mir-17-P1c Gja-Mir-17-P1c Hsa-Mir-17-P1c Lch-Mir-17-P1c Loc-Mir-17-P1c Mdo-Mir-17-P1c Mml-Mir-17-P1c Mun-Mir-17-P1c Oan-Mir-17-P1c Ocu-Mir-17-P1c Pbv-Mir-17-P1c Rno-Mir-17-P1c Sha-Mir-17-P1c Spt-Mir-17-P1c Sto-Mir-17-P1c Tgu-Mir-17-P1c Xla-Mir-17-P1c3 Xla-Mir-17-P1c4 Xtr-Mir-17-P1c

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Vertebrata

Genome context
(mm10)

chrX: 52742505-52742563 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-17-P1c)

Mir-92-P2c chrX: 52741697-52741761 [-] UCSC Ensembl
Mir-92-P1c chrX: 52741853-52741913 [-] UCSC Ensembl
Mir-19-P2c chrX: 52741991-52742056 [-] UCSC Ensembl
Mir-17-P4c chrX: 52742121-52742181 [-] UCSC Ensembl
Mir-17-P2c chrX: 52742341-52742403 [-] UCSC Ensembl
Mir-17-P1c chrX: 52742505-52742563 [-] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

UUACACUCCUGGAGUAUGCCUUGGCCAUGUCAAAGUGCUAACAGUGCAGGUAGCUUUUUGAGUUCUACUGCAGUGCCAGCACUUCUUACAUUACCAUGGUGAUUUAAUCAGAGGCCGCU

Get precursor sequence

Structure

        10          20        30         40        50         
UUACACUCCUGGAGUAU--   U   CC    CA-|      AA  G     G   CUUUU 
                   GCC UGG  AUGU   AAGUGCU  CA UGCAG UAG     \
                   UGG ACC  UACA   UUCACGA  GU ACGUC AUC     U
UCGCCGGAGACUAAUUUAG   U   AU    UUC^      CC  G     -   UUGAG 
       110       100        90        80        70         60

Deep sequencing

Go to detailed chart

Comment

There is a second Dicer cut +1 on the 3p arm.

3' NTU

Motifs

UG at 5p(-14)

Tissue expression

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Mature sequence

Mmu-Mir-17-P1c_5p

mirBase accession

MIMAT0000385

Sequence

0- CAAAGUGCUAACAGUGCAGGUAG -23

Get sequence

Proposed targets

microrna.org: MIMAT0000385
TargetScanVert: mmu-miR-106a-5p
miRDB: MIMAT0000385

Star sequence

Mmu-Mir-17-P1c_3p*

mirBase accession

MIMAT0017009

Sequence

36- ACUGCAGUGCCAGCACUUCUUAC -59

Get sequence

Proposed targets

TargetScanVert: mmu-miR-106a-3p
miRDB: MIMAT0017009